Wang Group

N-Glycosylation is one of the most ubiquitous posttranslational modifications of proteins in eukaryotes. The Wang Lab is working at the interface of chemistry, biology, and immunology with a focus on the structures and functions of N-glycans, N-glycopeptides and N-glycoproteins. The covalent attachment of glycans adds a new level of structural and functional diversity of proteins and expands the biological information of an otherwise concise human genome.

Postdoctoral fellows and students in Wang group explore concepts and tools from various fields including synthetic chemistry, molecular biology, structural biology and immunology to understand the functional roles of glycans and glycoproteins in biological systems (host-pathogen interactions, symbiosis, and other important biological recognition processes). The group is also interested in translating the knowledge gained from functional and mechanistic studies into the design and development of more efficient therapeutic agents and vaccines against cancer and infectious diseases.